Vol. 7, Issue 2, Part A (2025)

Psoriasis is a chronic autoimmune disorder characterized by persistent inflammation of the skin and joints, exerting a profound impact on physical health, psychological well-being, and social functioning. Its prevalence varies across populations and is influenced by hereditary predisposition as well as environmental triggers such as infections. Clinically, it most often appears as symmetrical erythematous plaques covered with silvery-white scales, predominantly affecting extensor regions. Although considerable progress has been made in understanding its genetic and immunological mechanisms, the disease remains complex and its etiology is not fully clarified. Conventional therapies, including corticosteroids, immunosuppressants, and biologic agents, provide symptomatic relief but are limited by side effects, high cost, and variable long-term outcomes, thereby increasing interest in complementary approaches. Ayurveda, with its longstanding use of medicinal plants possessing anti-inflammatory, antioxidant, and immunomodulatory properties, offers a holistic system of care that may complement modern medical strategies. The present clinical study was conducted to evaluate the role of Bruhanth Dhanthapala Thailam in the external management of psoriasis (Eka Kushta). The formulation, consisting of Wrightia tinctoria, Psoralea corylifolia, Celastrus paniculatus, and coconut oil, was administered over 60 days, and patient outcomes were assessed using erythema, induration, scaling, and area weightage as clinical parameters, supported by PASI scoring for overall severity. Preliminary observations indicate encouraging improvements in symptom relief and reduction of PASI scores, suggesting that the formulation may be effective in psoriasis management. The findings underscore the relevance of integrating Ayurvedic formulations with modern clinical evaluation to provide a safe, cost-effective, and patient-centered approach, contributing to more comprehensive and personalized strategies for the treatment of psoriasis.