Vol. 7, Issue 1, Part A (2025)

The objective of this research was to formulate an herbal gel incorporating extracts of Moringa oleifera and Aloe Vera and estimate it for its antibacterial exertion. The inflammation of pilosebaceous follicles in the skin leads to acne vulgaris. The exertion of certain bacteria species, similar as P. acnes, S. epidermis, E. coli, and S. aureus causes it. The development of antibiotic resistance by these bacteria and the side goods associated with current treatment rules demand the preface of new remedial agents for acne vulgaris. Moringa oleifera and Aloe Vera are herbal products that can potentially treat certain affections. One of its benefits is its antibacterial exertion. The hydroalcoholic extract of Moringa oleifera flowers was done by the process of maceration. Followed by assessing the extract's phytochemical ingredients, total phenolic and flavonoid content, antimicrobial exertion, and ash values. The topical herbal gel was formulated using 1% Moringa oleifera, Aloe Vera, and 1.5% Carbopol and the expression was subordinated to microbial assay also other evaluation tests similar as pH, density, physical stability, HPTLC, etc. were studied. The results of the phytochemical analysis show the presence of phenolics, flavonoids, tannin, steroids, and in Moringa oleifera extract. The extract and gel were active against the S. aureus and E. coli. No changes in color, odour, unity, thickness, or pH were observed, and the antibacterial exertion was retained throughout the storehouse period. The potent antibacterial exertion in a topical herbal gel expression indicates its viability as a volition to being an agent in managing acne vulgaris.