Anacyculus pyrethrum also called as Akarkara, is a perinnial herb that grows in the Himalayan. Anacyculus Pyrethrum root have unique ayurvedic value. The other parts of this herb possess insecticidal property. Anacyclus Pyrethrum is used in South Asia to treat toothache, facial neuroglia and chronic catarrh. Basically, Anacyculus Pyrethrum (Akarkara) is described in unani system of medicine as a great drug used in various purposes. In Akarkara medicinal part is root, It have pungent taste and are slightly aromatic. Which has considered as tonic used in remady since ancient times, to aid the nervous system. The main contribution of this work is to study herbal application and biological study of Anacyculus Pyrethrum. This review will help us to understand multidimensional uses of Akarkara and helps to futur study.