In the present review on Tulsi, an effort has been done to Medicinal properties of Tulsi. The therapeutic uses of plant are considered as safe, inexpensive & efficient as their ease of availability. The basil plant consumed herbs, Ocimum genus in plant family Lamiaceae. Tulsi to be effective for diabetes, The Rama Tulsi is the effective remedy for the severe acute Respiratory Syndrome. Juice of its leaves gives relief in cold, fever, bronchitis and cough. Tulsi oil is also used as the ear drop. Tulsi helps in curing malaria. It is very effective against indigestion, headache, hysteria, insomnia and cholera. The fresh leaves of Tulsi are taken by the millions of people every day. Tulsi reduces stress, enhances stamina, relieves inflammation, lowers cholesterol, eliminates toxins, protects against radiation, prevents gastric ulcers, lowers fevers, improves digestion and provides a rich supply of antioxidants and other nutrients. Tulsi is especially effective in supporting the heart, blood vessels, liver and lungs and also regulates blood pressure and blood sugar. Recent studies suggest that Tulsi may be a COX-2 inhibitor, like many modern painkillers. Tulsi improves the body's overall defence mechanism including its ability to fight viral diseases. It is good source of vitamin A and C, Calcium, Zinc, Iron, Chlorophyll and it possess antibacterial, insecticidal properties. In different parts of the world, several types of basil are cultivated, some of the widely used varieties can be categorized in two groups – holy basil and Mediterranean basil.